Uzgen (also Ozgon or Ozgon) is a town in Osh Province, Kyrgyzstan. It is the capital of Uzgen District. It is located at the far eastern end of the Ferghana Valley, upstream of the point where the Kara-Darya enters the valley. It is 30 miles northeast of Osh, and 20 miles southeast of Jalal-Abad on the banks of the Kara-Darya .
The town is mentioned in Chinese annals of the second century BC. It was one of the capitals of the Karakhanids, who called it Mavarannahr and left three well-preserved mausolea.
Uzgen lies on the ancient Silk Road trade route. In the center of town, there is a minaret and a mausoleum, which are both over 800 years old. These structures were built during the Karakhanid era who occupied Uzgen during the 10th through the 12th centuries. The Karakhanids brought Islam to the region, which is still the predominant religion today. During this time, Uzgen was a thriving economic and cultural center. The Karakhanid era ended when Ghengis Kahn's armies invaded the area.
However, Uzgen continued to thrive under the reign of the Golden Hoard. After Khan's empire disintegrated the region was left war torn. Uzgen lost its prowess as a Silk Road trading city and became merely a village. It remained in this condition until the area was brought under the protection of Tsarist Russia. In 1918 Uzgen entered the newly formed Soviet Union.